The real problem is not the fines, but to comply to all of them.
For example, EU article 13 has a direct impact on my product (my users can upload custom resources). Good thing that Belgium didn't implement it yet. But when they do, I probably need to move my business to Delaware or something.
They claim that article 13 is to reign in the big companies like YouTube. But in the end this also makes sure that EU has a hard time of building their own YouTube.
Anyway, I looked into it, and it seems possible for me to move my business abroad when we get that far.
But all this basically proves my point. It's easier to build a startup when you are outside of the EU.