It's not clear to me that folks would want this behavior globally - I personally would not, because sometimes I want to be able to include curly braces in my strings without it being interpolated, and I prefer the current syntax of having that just work. I'm very comfortable with having to add the 'f' to the string syntax to declare that this particular string should be interpolated.

There are other issues you'd have to deal with as well. Would you interpolate non-literal strings (e.g. in the code `print(input())`, if the user inputs the string "{1+1}", what would be printed?)? How would you propose dealing with jinja and other strings that typically contain curly braces that should not be interpolated? This could also be an issue with (potentially long) strings containing lots of random characters: if a '}' showed up in a string somewhere after a '{', even if separated by tens or hundreds of characters, then you'll run into errors. This could be a problem if you're dealing with pseudorandom or base-92 encoded strings, or even just strings representing code (imagine a python library that generates C++ or Java code which has lots of hard coded strings with braces).

I think overall, having to specify that a particular string should be interpolated is a better solution than having to specify that a string should not be interpolated.