> For which percentage of users?

Anyone using software that benefits from vector instructions. That includes a variety of compression, search, and image processing algorithms. Your JPEG decompression library might be using SSE2 or Neon. All high-end processors have included some form of vector instruction for like 20+ years now. Even the processor in my old eBook reader has the ARM Neon instructions.

Any users who either wants performance or uses a language that can depend on a fast library.

Why would it be irrelevant? Even the paucity of availability isn't really a problem - the big winners here are server users in data centers, not desktops or laptops. How much string parsing and munging is happening ingesting big datasets right now? If running a specially optimized function set on part of your fleet reduces utilization, that's direct cost savings you realize. If the AMD is then widening that support base, you're deeply favoring expanding usage while you scale up.