You'd be surprised how clean some of these things are, especially so if you don't plan on blowing things up big. Plus, with NR software these days, you can easily get usable 12,800 ISO & 25,600 ISO shots if you expose them well.
The real trick to shooting in low-light is nailing the exposure; too dark and you'll have dirty highlights, too light and you'll have blotchy, noisy shadows.