The rough polygon of Idaho - California - Arizona becoming less habitable every year. Mass migration to the east, water wars between wealthy landowners using most of dwindling water supply for agriculture and the rest of the population for drinking.
I'm not expecting some doomer apocalyptic scenario. But every year, it'll get 1% worse. People will struggle 1%, there will be 1% more resentment between race/class/demographics, 1% more people leaving, and so on. It'll just get worse.