The China/Pakistan border clashes have resulted in fatalities on the order of several dozen in something where neither nation really wants to escalate. Ukraine would have long since lost this war if not for the US directing the funneling tens of billions of dollars worth of weapons, training, and so on to Ukraine. This support has been directly responsible for the excess deaths of Russians and Ukrainians alike numbering in the tens of thousands.
Not only is this orders of magnitude more impactful than the other conflicts, but perhaps even more concerning is what in the world the endgame might be? By effectively throwing its entire influence into this war, the US has now effectively staked that influence on the outcome of the war. And it's the exact same situation for Russia. The two most nuclear armed nations are now in a conflict that is a must-win for both of them.
IMO this conflict ending up going nuclear is still highly improbable, but highly improbable is far closer to nuclear war than we've ever been.