In the most general form, ideologies which include an orthodoxy-heresy dichotomy in assemblage out-compete those which don't. The development of orthodoxy itself was a quantum leap in the progression of human thought, and it contributed to both the spread of early Christianity as well as the hatred toward it in (late)-antiquity as its adherents were perceived to be annoyingly self-righteous.
Orthodoxy-containing ideologies characteristically participate in a hegemonic form reality building. But, basing ethical judgements about a particular ideology singularly on whether or not it contains an orthodoxy-heresy component is a poor measure. There are better arguments than, "I'm against the orthodoxy" or "this person is a heretic."
Instead, I maintain that ethical judgements of ideologies should be based on their material outcomes, though this often overlaps with judgements involving the grounding of what makes someone an adherent or heretic, the material benefits granted to adherents of the orthodoxy, and punishments to which heretics are subjected.