Purism explicitly put Linux support first, unlike Framework. Suspend is flawless, any flavor of Linux should work out of the box, including FSF-endorsed distros. Default PureOS is FSF-endorsed. The devices require no binary blobs whatsoever, even for WiFi.
Purism explicitly prioritize security (https://puri.sm/security) and privacy (https://puri.sm/posts/tag/privacy/), unlike Framework. Intel ME is disabled (for Librem 15, also neutralized), hardware kill switches are really convenient. First class Qubes support, it can even be preinstalled (it's what I use).
Most important things are repairable/replaceable: battery, WiFi card, RAM, SSD, screen (I think). I heard keyboard is hard to replace though, but I had no problems with it. The keyboard is great, but the touchpad is worse than the one in Macs. I use a mouse. The laptop is thin, beautiful and powerful for my tasks.