One of my ex-colleagues was hired straight out of university by a company and he did not take a single holiday in 4 years because his boss would always try to make him feel guilty or would imply that there would likely be negative consequences for him as an employee.

After he eventually quit and changed companies, he had very low expectations and he couldn't believe how much better that second company was... It was a startup so it wasn't exactly low-stress by my standards; it goes to show how extreme the differences can be between companies that even a job which I considered challenging seemed like a walk in the park to him given what he had experienced before.