From what I've heard (including from acquaintances who have worked there), a job at an Amazon Warehouse takes a toll on your body for sure. For sure it's hardly alone in being like that.
(The people in my extended social circle who are in jobs involving physical labor are perhaps more likely than most physical laborers to have people in their social circle who sit at desks, and to be able to access networks and resources to shift out of physical labor to make a living).