At top levels it gets closer -- often human play is compared to engine play and people will discuss which moves were 'engine-like' vs 'human', and a significant achievement would be to play the engine moves on every turn. Although it should be said that engine moves are not always necessarily the best moves positionally, nor the moves with the highest win % versus a human (because you can 'trick' a human, whereas the engine can't trick itself so it will never prefer a move like that)... but they are always the best moves tactically.

In middling ratings, if I was allowed to look at the engine (in a Lichess replay for instance) I'd guess I can tell a player using the engine with 99+% accuracy. People _always_ lose on tactics (or misplayed opening lines, misplayed endgames, etc). Engines never do. At high ratings I assume this goes down, especially if the players are playing 'boring' draw-ish lines, in which the best moves are fairly obvious most of the time.