In terms of actual features, Transmission is more lightweight. It doesn't support super-seeding, broadcatching, native SOCKS support and doesn't have built-in search engine integration.
If you want to go that route you might as well use Deluge, which is built on the same libtorrent library, has a proper daemon-client architecture with fully featured native clients for all major platforms.
This is true but for me this is a disadvantage. qBitTorrent allows to fine-tune a lot of settings. Not as many as Tixati but still.