It makes it seem as if using just protonmail could result in deleting a wrong email. This is not the case, you have to be using proton bridge.
People who care about protonmail but don't care about proton bridge have to click the link to learn that.
UIDs get desynced between IMAP client and bridge, as the bridge does not seem to use persistent UIDs for messages.
If you don't use the bridge you won't have issues with mismatched UIDs.