> Unless the VC gets caught with their pants down right at the end of the transition, they'll probably turn a profit.
Sure, it's like investing in stocks. But the incentives for VCs and academics are totally different. In academia, volume is a big part of prestige (not for everyone, of course, and to many people's dismay), whereas for VCs they're looking for that one huge disruptor, and are often willing to miss on hundreds to hit it.