I've experimented taking a rooted Quest 2 on flights before and have enjoyed it. 6DOF is a bit of a problem, but watching movies and non movement based games are great.
Apart from the flailing limbs and suddenly-rotating head with apparatus. Eliminating those, are we back to just watching a movie? That said, I'd much rather watch a movie on a plane in a VR headset than off of a seat back.
Watching a movie in VR on a flight beats the hell out of the crappy headrest TV. A 2 hour flight turns into a 2 hour experience in a full size movie theatre. The seats are fairly similar so it would probably add to the immersion. With good noise cancelling headphones you might even forget you're on a plane.
I mean, there are other applications for VR that might make sense for spatially limited situation like a flight is. On some planes I couldn't even open my laptop properly. With VR you might have lots of screens.