With IPv6 instead of NAT deciding that port 2000 maps to 192.168.1.3 port 22, you have a firewall that may or not choose to route to xx:yy:zz or not, and to allow an incoming connection over port 22 to that host or not.
If you don't want to accept incoming connections to a given machine or network on IPv6 without NAT that's very easy to have.
Now, sometimes NAT is needed anyway: QubesOS supports IPv6 using NAT because it splits things up into many different VMs on one computer. But that's a pretty rare case.