It's quite common to feel afraid of the new: it's an essential survival mechanism. However, just because we get that feeling initially, doesn't mean we should always trust it over a lived experience. People for all time have experienced this feeling when doing something new: riding a bike, driving in a car, and first week of kindergarten. What makes us the hyper adaptable omnivores we are is our ability to become desensitized via repeated exposure to things that aren't real threats.
And of course, sometimes we've gotten complacent and made an error, like lead in gasoline. But that's why we study everything to try to ensure we are improving.