It’s possible to do a lot of damage with heavy drinking, yes, but it’s not true at all to suggest alcohol is the most damaging drug. There are numerous synthetic drugs that can produce long lasting damage or even death even in experienced drug users who believe themselves to be consuming responsibly.
https://en.wikipedia.org/wiki/Desomorphine
> While desomorphine was found to be faster acting and more effective than morphine for the rapid relief of severe pain, its shorter duration of action and the relatively more severe respiratory depression produced at equianalgesic doses, as well as a high incidence of other side effects such as hypotension and urinary retention, were felt to outweigh any potential advantages.[15][16]
From [15] we have: short duration which is independent of dose, tolerance, persistent decrease in respiratory rate, <when used to treat severe chronic pain> less sleep compared to morphine, possible greater withdrawal symptoms than morphine.
For medical uses [15] cites some good uses where it is preferable to morphine, but this is a drug that's even more worthy of regulation than morphine itself.
I find in general drug discourse making these comparisons isn't super helpful. The risk and damage profile of different drugs is very complex. Mdma in frequent use isn't very damaging in one sense, but can really impair cognitive function long term which can reduce quality of life as much as liver damage of drinkers or COPD of heavy smokers (as a simplified illustrative example)
I think presenting a view that all things are toxic and that healthy use of anything is down to how, why and when it is used is better for normalising the conversation rather than doing X vs Y showdowns.
