How much will you make from selling it? Just use it as a regular PC.
Ideas:
Install Gentoo (not a joke! I have a 22 core CPU and it really helps)
Do heavy video processing.
Get a 4 channel TV Tuner card and a lifetime Plex membership, and use it to DVR OTA broadcast. Transcode them, which is where a beefy machine comes in - the default ts format takes up too much space. Lots of good shows on PBS. And as much as people complain about Plex, there is no good substitute for their DVR service.
Can the GPU be used for ML applications? Things like Stable Diffusion? If so, go wild with it.