AFAIK it’s nothing to do with Intel/Arm swap over.
macOS in recent years dropped support for antialiasing because Apple (+ the UltraFines they sold) displays are all[1] high dpi.
The other issue with a PPI of 150 is you’ll likely end up needing to use a non-evenly scaled resolution to get things “sized” right, so even basic things like a 1px line won’t be crisp, because it won’t be rendered as 1 solid pixel.
1: Yes I know the 24” 4K isn’t quite the same “high dpi”.