Not sure why you are trying to invoke shame for something that is a well-known effect of economic conditions, and which has been observed to change with those conditions much faster than (and likely driving rather than driven by) cultural change.
> America had 100,000 people die of drug overdoses last year, whereas societies that shame people for drug use have far lower rates of overdoses.
So do countries that shame people less, like most of the rest of the developed world.
> Middle eastern and south Asian countries that shame people for pre-marital sex largely managed to avoid the AIDS epidemic that gripped similarly poor countries in other regions.
Which is some good luck for them, but one of the reasons it spread so much and i nterventions were so difficult jn Africa was strongly shame-centering cultures interfering with both prevention and treatment (and even acknowledging the fact and nature of the problem.) So, kind of not helping your argument.