steep learning curve if you've never used a split\ortho board but once you learn how to type again (couple of weeks for me), other than that my wrist pain is now gone!
only real downside is people asking why I have a pair of glowing oven gloves on my desk
I'd like to add that switching to a drastically different keyboard is the perfect opportunity to simultaneously switch keyboard layouts if thats something you've been considering. I switched from QWERTY to a layout based on Programmer Dvorak when I got my Moonlander. I'm really glad I did.
This was exactly my line of thought when I got the Moonlander (except I thought Colemak). It has been gathering dust in my shelf for almost 2 years now.