I've spent enough time in the shady parts of the internet to realize that people that spend significant time learning about niche/dangerous hobbies _tend_ to realize the seriousness of it.
My fear with bio-weapons would be some 13-year-old being given step-by-step instructions with almost 0 effort to create something truly dangerous. It lowers the bar quite a bit for things that tended to be pretty niche and extreme.