If you encrypt it, this is no longer possible. If a cheater wants to decrypt it, he has to get access to the decryption key, which usually is send over an TLS encrypted connection (with certificate pinning in place) [Or in some cases self made encryption :/].

Therefore he has to either reverse the game to get the certificate or has to attempt to read it while the game is running. In the first case the game developers (and the Anti-Cheat providers) will try there best by obfuscating the specific regions. And the 2nd case is basically what AC is all about, and therefore difficult for modern Anti-Cheats.