I did upgrade to an LTO-5 drive last year so so, after finding a new-in-box from a liquidation sale for something like $450. The nice thing about LTO is that it's 2 Generations R/W and 3 Generations Read - so the LTO-5 drive will Read/Write LTO-5 (1.5 TB) and LTO-4 tapes, and read LTO-3 tapes. I think with one of the new standards (LTO-8?) it's a bit more muddy, so check compatibility.
I think that LTO-4 and LTO-5 is the sweet spot for hobbyists: You still need to spend some money on a drive or two and buy brand new tapes, but it's reasonably affordable. That said, for a business, I'd just bite the bullet and buy a new drive. Dell sells an external SAS LTO-7 drive brand new for $3700 list price, but I think there might be cheaper options. Together with some tapes and a SAS Controller, I'd say that for $5000 you can get a decent, brand new setup.
I put the tapes in Turtle LTO Cases (https://turtlecase.com/products/lto-20-black), and they sit in a closet. It's not climate controlled or anything, but the place is roughly at a similar temperature year round. The tapes aren't THAT sensitive, but I'd definitely not store them in the garage where I might get a 50+ degree temperature difference throughout the year. That said, there are companies that offer off-site storage options with climate controlled environments. I haven't looked into their pricing since I didn't need it, but the nice thing about tapes is that you can just backup to two tapes and send the second tape off-site. LTO has built-in encryption support, so that's an option.
Twice a year or so, I run a restore of the tape and compare it to the SHA256 that I took while backing up the file (I did build myself some rudimentary cataloging system to SHA256 hash every file, then back it up to tape with tar, and make a record of what file with what SHA256 got backed up when on what tape). I've yet to encounter any bit rot/defective tape issues, but YMMV.
I do use Backblaze's B2 service as well for cold-ish storage. Though I only back up truly irreplaceable or inconvenient to recreate data into B2. That way, I have multiple copies of truly important stuff, I have stuff readily available where I am, and I have terabytes of stuff that isn't worth the expense for the cloud since I can re-create it, but nice to have a copy of.
Tape Drives may be overkill for many and external hard drives (plural!) might be a better option for many. What I like about tape drives is that the media isn't "hot". If I have ransomware running wild, connecting an external hard drive puts everything on it at risk (hence the need for multiple drives), whereas with a tape, it would have to specifically try to rewind the tape and start overwriting, and I would notice it. But YMMV, I never had a ransomware problem myself, but I do have stuff I really don't want to lose, so multiple backups of it in multiple ways (Daily .tar archive on a hard drive, backed up to tape, and backed up to the cloud) should hopefully give defense in depth and the ability to at least recover some older state.