Uhm, yes, I think it is a problem because unfairly losing isn't as fun as fairly losing or fairly winning. Ignorance about the fairness of a game may work in a few instances but would not scale.
You don't have to reach pro levels, it often only takes small assists to turn a balanced game on its head, ruining someone's experience with a game. Repeat often enough and the userbase will leave, feeling cheated or at least demoralised for being unable to compete or improve.
And allowing machine-assists, thus leveling the playing field, turns the game into a completely different one that is (imho) drastically less fun whoever may not be interested in (or may be unable to) running/coding their bot.