I read a great article about the making of the show and there were many real-life stories they couldn't include because they felt people wouldn't believe it was real.
I think their go-to example was meeting up with a Google X person in their offices and that person getting huffy about something or other and then trying to storm out. But then they had trouble with their keycard so there was that awkward pause because they couldn't just storm out and slam the door. Best part was that they were on inline skates (and rocking a pony tail!) so it was a totally Mike Judge perfect moment - weird silent tension as pony tail skate master is trying to beep himself out of the room.
I've definitely seen and heard about lots of strange things in SV that people simply wouldn't believe if they heard it.