I would not be so sure.

What's the point of the theoretically perfect solution when the travel times are so unpredictable? The truck stops are 3-5 minutes apart on average (according to random reddit comment [0]), 1% of that is 3 seconds. Meanwhile a single missed light (say because some other vehicle was driving slow or UPS driver was guided into non-familiar route) can add more than a minute.

So something like a better way to arrange packages in truck, or better traffic preidiction model, would be much more useful than any TSP improvements.

[0] https://www.reddit.com/r/UPS/comments/89zw0h/how_long_does_o...

The problem is that in practice, you don't have complete information, and the information you have is slightly incorrect. You also don't have a complete model, and the model you have is slightly incorrect.

Throw on a few more decimal places if you like. The point is that in the physical world, “best” isn’t usually categorically different from “extremely close to best with high probability”.