Concerns over reliability? Some car issues can be erratic and you may not find out about them until some time later. If you buy used, there's a level of risk regarding what the car's been through with previous owners. If you have a family and/or work with a tight schedule and/or park in areas where you wouldn't like to be left stranded, you may really value reliability.
You've never heard of a brand new car going wrong? A used car that's been on the road for 10 years with a full maintenance history gives me more hope for reliability than a brand new car that hasn't had time to reveal its problems. You can always pay someone to insure you against unlikely events and they don't care at all whether the car is new or not. It's up to you to decide how much risk you want to take.