I understand the “structural tilt away from densely populated states” to be a different thing than gerrymandering. Whichever party outperforms in sparely populated rural states (historically, it was democrats) has an advantage under the US system.
The point that directly elected executives give rise to different political dynamics is no less objective. Among those political dynamics is the feasibility of blasting a nationwide message that embodies the party in a person low information voters can relate to. That’s been a major enabler of Democratic machine politics aimed at immigrants. And these days, it’s an enabler of MAGA machine politics.
It’s quite different in Westminster style parliamentary statements, where people in different districts vote for different candidates.