I have.
On a Mac Studio with NixOS based Asahi Linux and 128Gb of RAM, mixtral 8x7b uses 49GB of RAM. At the same time I load airflow tasks that deal with world wide datasets (using ~60GB on 16 parallel streams with the performance cores) format is parquet and also mmaped.
Computer still has 8 efficiency cores and the whole GPU for visualizing the maps using lonboard / browsing / etc.
The computer uses 8-10W when idle, ~100W when running jobs or actively using the LLM and around ~200W when really using the GPU.
This makes it very efficient energy wise in my book compared to the beast of keeping a modern CPU and nvidia GPU on when idle. My electricity bill is unaffected.