The curse of "zero cost abstraction" strikes again :/ A 5x performance difference between debug and release mode isn't uncommon in C++ either and a real problem for game development (plus the slow build times, but those two problems go hand in hand - you can have "high-level abstractions" that build slowly and run fast, or build fast and run slowly).
That's why there's so much advice to write C-like C++ and also ignore the stdlib in gamedev circles. The Rust equivalent is probably to write "embedded style Rust".