I agree that it wouldn’t stop this library from injecting backdoors into decompressed executables. But I still think it would be a big help anyway. It would stop this attack from working.

At the big picture, we need to acknowledge that we can’t implicitly trust opensource libraries on the internet. They are written by strangers, and if you wouldn’t invite them into your home you shouldn’t give them permission to execute arbitrary code with user level permissions on your computer.

I don’t think there are any one size fits all answers here. And I can’t see a way to make your “tainted output” idea work. But even so, cutting down the trusted surface area from “leftpad can cryptolocker your computer” to “Leftpad could return bad output” sounds like it would move us in the right direction.