I think everyone's got a different threshold for where returns start diminishing sharply. While I'm squarely in the "don't waste time micro-tweaking your editor" camp, there are some little bits of shortcuts and tooling that made me much more fluent at code-editing with very little investment. One example that stands out is the multi-cursor support that Sublime Text popularized (and which I use all the time in vscode now). It eliminates a good 80% of repetitive typing, or symbol refactoring that would have involved clunking through menus in old IDEs, and makes experimentation that much quicker. Feels fundamental, like copy/paste shortcuts which everyone knows now.
Yes, I tend on the side of only tweaking things when I realise I'm repetitively using the same context menus. That's the only point I learn the keyboard shortcuts, or map one, these days. I really haven't had to learn too many shortcuts. The best ones are multi-cursor editing like you've mentioned.