My cat has been in the feline equivalent (Solensia/frunevetmab) for about two years, and although it had a huge positive impact for the first 12 to 18 months, it seems to have suddenly completely stopped working in the last little while.
One theory is that the immune system eventually starts attacking the monoclonal antibody med itself, another is that as in humans, the OA progression might accelerate under the drug.
