Ask HN: What are the best practices in managing corporate email and setup rules

Asking Managers and VPs: What are the best practices to stay on top of hundreds of emails that are coming daily to your mailbox? How your mailbox filtering rules look like? How you setup your folder structure? How you later so daily thru your emails? How you keep track of all required follow-ups or work you need to do?

What worked for you and what did not? Please help sharing your strategies and ideas. Greatly appreciated!!!