You can't turn material into "nothing". At best you can turn it into equivalent amount of energy if you collide it with antimatter.
That being said I don't really feel the difference between "vaporisation" and "disintegration". In both cases you stop being biology and start being physics in a subjective instant. (at least from the perspective of your own central nervous system, which has not enough time to even detect that something has happened)
In both cases you go from a living, breathing, laughing, thinking human being into contaminants in the air or surfaces around you.
What do you feel is the difference between "vaporisation" and "disintegration"? Is it about how big your largest continuous chunk is? Where do you draw the line?