Let's recap.
You:> A calendar isn't a bad idea, but I assume GP has ways of making sure they do all those other things. What's different about a domain registration?
where "all those other things" are paying a mortgage, going to work, paying utility bills, getting food, putting gas in your vehicle, etc.
2.5 hours later, HeatrayEnjoyer responded:
> Those examples have tangible real world effects before they become permanently irreversible.
An hour later you then said:
You:> And losing access to your email/other domain assets doesn't have "tangible, real world effects"?
At this time, a mere 3.5 hours after your question you seem to have forgotten that you asked it. If you had remembered that they were answering your question, which to remind you (in case you've forgotten it again over the course of reading this comment) was how do people make sure they do those other things yet forget to handle domain renewal.
You would then have realized he's not saying that losing a domain doesn't have tangible, real world effects. He's explaining that the difference is the timing of those effects.
In fact many people do sometimes forget to do those other things. But those other things are all easy to correct with little or no negative consequences when they forget so the penalty is small for not developing an ironclad system to never forget them.
For example if they forget to pick up groceries on the way home from work and then the next morning find that they don't have food for breakfast the consequences might be something like they have to skip breakfast that day if they don't have time to go out for food before they have to be at work.