I was using iTerm up until about a week ago when I unboxed a new Mac and decided to test out alternatives while setting it up. Ghostty wasn't out yet so I started with Wezterm, and was shocked to find how much it's speed improved my terminal experience. Typing latency is much better in nvim, and scrolling is vastly improved in nvim and tmux.
Ghostty feels like a Mac app like iTerm2 while being fast and having fewer features. Wezterm feels more like an app ported from Linux, but has a much richer config system and features like build-in multiplexing which means it's replaced tmux for me - while keeping all my tmux keybinds.