However, I feel eye strain from doing it, so I prefer other methods. 99% of the time, I do https://en.wikipedia.org/wiki/Blink_comparator instead, just switching between two images with zero flicker and zero displacement offset. Also with both eyes, it's easier to spot certain kinds of subtle differences like color shifts, JPEG-like compression artifacts, tiny differences in antialiased renderings, etc.
One benefit of the cross-eyed method, though, is that you can difference videos. But the use case for that is rarer than differencing images.