Pipx is a tool for users to install finished applications. It isn't intended for installing libraries for further development, and you have to hack around it to make that work. (This does gain you a little bit over using Pip directly.)

I just keep separate compiled-from-source versions of Python in a known, logical place; I can trivially create venvs from those directly and have Pip install into them, and pass `--python` to `pipx install`.

>With Python it is pip, poetry, pip search no longer working, pipx, and now uv (I probably forgot some things).

Of this list, only Poetry and Uv are package managers. Pip is by design, only an installer, and Pipx only adds a bit of environment management to that. A proper package manager also helps you keep track of what you've installed, and either produces some sort of external lock file and/or maintains dependency listings in `pyproject.toml`. But both Poetry and Uv go further beyond that as well, aiming to help with the rest of the development workflow (such as building your package for upload to PyPI).

If you like Pipx, you might be interested in some tips in my recent blog post (https://zahlman.github.io/posts/2025/01/07/python-packaging-...). In particular, if you do need to install libraries, you can expose Pipx's internal copy of Pip for arbitrary use instead of just for updating the venvs that Pipx created.