(the oral history is obviously a bit sketchy, but she used to tell me her father also caught TB - cholera maybe ? - when he was removing bodies from the flooded Balham tube station in 1940 - https://www.ianvisits.co.uk/articles/75th-anniversary-of-the...)
Well, I got quite the scolding about missing my jabs and a stern lecture about how many awful diseases have been cured because of vaccination. I could never forget how emotional she was about it.
To people born in the early 20th century, seeing the effects first hand of the vaccination programmes of the mid 20th century (not to mention antibiotics) must have seemed miraculous. I think we’ve lived without these diseases for so long that some people (stupid, selfish people) simply think they don’t exist or pose a threat any more.
This is true beyond just vaccines. All too often hardships are forgotten, history is just old pictures and stories, and people who are too far disconnected from those real events and don't learn from history will just walk the same path, leading to the same hardships.
They all think that the world is better today so they're smarter or better than the old generations, that the world evolved so they're intrinsically prepared, so the pains of the past can't harm them. Ironically they're ignoring all the lessons and the tools that made the world better and are needed to keep it like that, and instead think things are better because they just are.
They'll skip any vaccines or support extremist regimes because they think the modern world is just immune to this, it's intrinsically and permanently "fixed". We have freedoms or don't get sick because we "just" have freedoms and don't get sick.
Having close family spending a lifetime paralyzed by the polio virus before a vaccine was widely available, or spending some of my life in the cold embrace of dictatorship really drove the point home for me about learning the lessons of history.
The safety record of the BCG vaccine, in terms of permanent harm, is pretty good. But a normal side effect is "The usual expected reaction to BCG vaccination is redness and/or a small lump at the injection site, followed by a small ulcer (open sore) a few weeks later (usually less than 1 cm in diameter). The ulcer may last from a few weeks to months before healing to a small flat scar."[2] Mass vaccination will have parents screaming "my perfect baby has an open sore from the vaccine" on Instagram, with pictures.
The classic live-virus smallpox vaccine has similar side effects, by the way, plus a death rate of 1-2 per million.
Huge political problem. Remember all the screaming about the COVID vaccines, which are pure RNA, can't replicate, and have fewer side effects.
[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC3349743/#s6
[2] https://www.rch.org.au/uploadedFiles/Main/Content/immunisati...
That's so weird to me given that literally everyone where I'm from(Poland) has this on their left arm. Nothing to post on Instagram about. It's as universal as having a belly button - not having a vaccine scar on your arm would be the thing to post about if anything.
This is misleading. Vaccines, including those for covid, generally include adjuvants to stimulate the immune system [1]. While I understand the point your making here, the covid vaccines were not syringes with pure RNA in them.
[https://www.health.nsw.gov.au/Infectious/tuberculosis/Pages/...]
I got it when I was a toddler in the late 80s and I still remember the excruciating pain and have the scar to show for it.
I grew up in the third world. I have never met a Westerner with this scar unless they got it in the sixties.
Why is this?
There's an old Dutch fort in Ghana with a graveyard. Prior to modern medicine white people dropped like flies in Africa.
There will always be some small percentage of your society that refuses to accept what is taught in school. The US has it bad because we've had multiple "Great Awakenings" that resulted in literal cults that grew to national size (mormonism, Church of Christ scientist, Jehova's Witnesses, thousands of various "Evangelical" fundamentalist sects) that all take as a foundational belief that the entirety of modern science is a massive cover-up to prevent people from knowing about god. They explicitly believe that scientists are Evil, and in league with Satan to keep them from god.
Fully ten percent of the American public for the past 50 years, or 30 million people believe "God created human beings in their present form at one time within the last 10,000 years"
Those people have always been good at organizing and have groups that are extremely motivated because they genuinely believe they are fighting a holy war against Satan. They have driven American policy for centuries, from the religious portion of the southern states insisting that god wanted black people to be slaves, to the Christians being a large portion of the temperance movement that resulted in Prohibition, to the current Book bans, to driving a significant amount of the political pressure causing Visa and Mastercard to threaten to ban pornhub (https://en.wikipedia.org/wiki/National_Center_on_Sexual_Expl...).
A huge percentage of flat earth believers for example are there because it is the logical endpoint of "you cannot trust any scientist because they are all in league to drive you away from god's light"
If 10% doesn't scare you, consider that the same insanity around a man named Kellog insisting in "purity of spirit", as in the religious meaning, is why 90% of White men in the US are circumcised. That rate is only comparable in Israel and nations with Islamic laws.
America struggles because of religion, specifically a breed of religion that insists you cannot trust any institution but it. Note how hostile the current admin was to a Preacher preaching peace.
Their preferred religion does not preach peace.
At least smallpox has been eradicated (except for potentially some bio weapons labs), so hopefully our stupidity won’t bring that back.
"Recorded history" has a very specific definition that places it in contrast with "prehistory": it's the time period in which we have written records of any sort, as opposed to the time period in which there is no surviving writing. That both phrases have "record" in them doesn't make them synonymous.
What’s a heinous tragedy in one could be an existential threat in the other.
Edit: actually let's put the 1950s up there instead. I think there's more information that way.
Additionally, from the article:
> the CDC started monitoring TB in the US in the 1950s.
When we say "recorded history" we don't mean "the window of time in which we have detailed records up to our modern standards", we specifically mean "the window of time in which we have records of any sort", contrasted with "prehistory".
The phrase they were looking for is "largest on record" or even better "largest since 195X".
> For broader world history, recorded history begins with the accounts of the ancient world around the 4th millennium BCE, and it coincides with the invention of writing.
EDIT: Downvote away, but I'd be interested to hear from someone who believes that "recorded history" is not incorrect and confusing usage here, with an explanation rather than a drive by vote.
An tuberculosis outbreak in Kansas has become the largest in recorded history in the US....the CDC started monitoring TB in the US in the 1950s.
"This is mainly due to the rapid number of cases in the short amount of time. There are a few other states that currently have large outbreaks that are also ongoing."
People with an active infection feel sick and can spread it to others, while people with a latent infection don't feel sick and can't spread it. It is treatable with antibiotics.
State public health officials say there is "very low risk to the general public."Treating it casually has led to widespread resistance.
https://en.wikipedia.org/wiki/Multidrug-resistant_tuberculos...
https://en.wikipedia.org/wiki/Extensively_drug-resistant_tub...
> People with an active infection feel sick and can spread it to others, while people with a latent infection don't feel sick and can't spread it.
https://www.who.int/teams/global-tuberculosis-programme/tb-r...
"Analysis of data from 14 countries in Africa and Asia suggests that about two thirds of global TB transmission may be from asymptomatic TB (95% prediction interval: 27–92%)."
I have long suspected this as part of why the subject isn't much discussed, despite being more prevalent than most realize.
The elephant here is (aside from latent infection) the atypically long duration of treatment, which can exceed 6 months and is harsh. Many, even otherwise responsible people, will founder before the proper end of treatment and this, I think, is what terrifies health professionals - so much, that it almost seems to be avoided.
It's probably time we start looking a bit harder for "natural" or alternate treatments. Some in medical journals, are under scrutiny, but inconclusive.
Edit: I also think we'll be finding more about latent infections being involved in an array of other ailments, especially when mixed with the ultra prevalent EBV. And EBV is involved in a lot.
We are looking, quite hard, in fact. Mycobacterium tuberculosis is among the most studied microörganisms.
Like HIV, it is notable particularly for being able to defeat the attempts of the immune system cells to kill it, and it in fact infects and reproduces within macrophages. Medical researchers have done a lot to understand how this is possible and we (as in humanity) have identified several enzymes and related biomolecules which seem to be crucial to this process, which we might be able to inhibit with a targeted drug.
However, all of this scientific research has the usual problem that it is very difficult and expensive. In order to inhibit the enzyme, the drug must be absorbed by the body, and then make its way into the macrophages, and then it still must be active, and have no other toxicity to the host. It is easy to say "just inhibit isotuberculosinol synthase", but it is much harder to do.
As I understand it, this is also the reason why treating tuberculosis requires such long courses of antibiotics. When treating a normal infection, we are basically just killing most of the pathogens, and we hope that the immune system will mop up the rest. In the case of M. tuberculosis, the drugs have to kill all of the bacteria, which is why multidrug therapy is basically always used and the patient must continue treatment long after symptoms seem to have disappeared. Even when patients have recovered, they are always considered to be at risk of still having latent tuberculosis, which is why hospital screenings often feature a question like "have you ever had a positive test for tuberculosis?"
Antibiotics are found in, and derived from, nature.
I was diagnosed with a latent TB infection received from a family member back in the early 1990's as a teen. I believe city and state departments of health must've tracked the "outbreak" back but I don't think it was ever on the news or made a big deal of. By the time we were diagnosed, the family member's symptoms weren't anything worse than their typical smoker's cough and was a heavy cigarette smoker anyway, not sure how active his infection actually was at the time but he never required hospitalization, just similar antibiotics, IIRC.
I was treated with Isoniazid (known as INH, one pill daily for a year), I never felt any symptoms from the infection or side effects from INH, they monitored monthly initially with skin prick tests then chest x-rays and after the year was up, I was done. This did prevent me from donating blood a few years after the infection was cleared; I assume there are still rules in place.
Neither the latent infection nor the year long treatment were harsh. IMHO, TB's a powerful but rather slow-moving internal infectant, and it was historically ravaging because of the earlier conditions of the world and lack of medicine at that time.
Is the idea that a different label would lead to higher compliance rates?
The fear is overblown. I've known multiple people do the 9 month treatment and none had issues. One person had tingling sensation and that was resolved by an increase in vitamin intake after consulting with a neurologist.
They were in their early to mid thirties. Most problems occur when older people take the medication.
You have to be a little suspicious of some of this — folks are looking for political reasons for scary disease outbreaks.
- TB physician since 2006
This is going to be a crazy four years, if it’s only four.
For the average for-profit company, the actual business the company does has no value beyond its ability to generate profits. The damage a disruption causes today can always be offset with higher expected profits in the future.
But for many government departments, the day-to-day business is the entire point. Any disruption can easily cause irrevocable damage. Even when the net outcome is positive, the gains often cannot offset the damage, because they go to different people.
1) state's rights
2) anti-science
3) a number of people in the administration (very possibly including Trump himself) thinking that the CDC is an example of "the deep state" that conspired to keep him from winning in 2020
But, hey, Joe made groceries more expensive and the administration didn't kiss enough rear on the left side of the Dems to get Kamala elected, so, here we are.
A less nuanced answer is the HHS/CDC made Trump look bad in handling the COVID-19 pandemic and so they’re now ordered to say nothing about anything ever again.
[1]: https://static.project2025.org/2025_MandateForLeadership_FUL...
I'm surprised people put up with it when there's a vaccine.
Poor countries and communities cannot afford the options on the market. TB wont be solved until we put people before profit.
Even for poor countries it's not much. In the UK when I had it they sent a nurse round to the school and all the kids lined up and they did like one a minute. Free to us lot of course on the NHS.
I think it was quite nasty and leaves a scar though.
It would be useful and highly informative to be able to visit a single page to see daily/quarterly/bi-annual/annual diffs of which efforts habe received signoff.
[0] https://www.unmc.edu/healthsecurity/transmission/2023/09/05/...
Appears that it originated within a family group involving 6 kids and 7 adults.
The original cases were in low income people who had been born outside the US but whose children were born in the US according to the paper.
Baffles me that someone would write something so definitively yet not expand on it in any way at all.
Not saying you're wrong (I have no idea), but what a low-effort comment. I'm curious, you seem (or claim, at least) to know something, can you help me satisfy my curiosity?
But unfortunately the current administration has decided an ideological purification is more important than keeping the American public apprised of threats to their health.
So it wasn't published last week, and probably won't be this week either. "Politics don't matter" though ;) Bummer!
If the ideology was what you're saying, then wouldn't they want to spread the info and blame it on the "dirty illegals" or whatever?
pretty sure the ideology is to remove every social safety net and service to "prove" government doesn't work and then the robber barons can swoop in and make it a paid service... and make it so the capital class gets to make and save more money as they can afford to buy any of those services that were cut. it's basically vulture economics but at the nation scale. it's not great.
Supply side Jesus is just alright.
We have good reason to believe it'd show up here given that Kansas's TB situation has had multiple bulletins over the years
Ofc, one may conclude anything one wants,
It's not a "rough start for HN", it's the current climate of the world through the lens of the US.
Unfortunately politics has infected areas of our lives we took for granted. The stopping of reporting coming out of the CDC/NIH/HHS makes discussing health science articles more challenging. And this is a direct result of the new administration. While this article may not be vaccine related, the new administration wants a known anti-vaxxer to lead the HHS.
I'm an old person. I have a leftist bent. I used to get along with many conservatives, I just had different policy viewpoints than they did. What we are seeing now is a completely different political landscape where one of the parties is actively setting up a dynastic plutocracy in the open.
FWIW I have a ton of criticism for the "other" party too as an ineffective mess sucking the corporate teet almost as hard, just without the actual proto fascism.
The resurgence of TB has been the big story in infectious diseases for a while now.
Globally:
> The World Health Organization (WHO) today published a new report on tuberculosis revealing that approximately 8.2 million people were newly diagnosed with TB in 2023 – the highest number recorded since WHO began global TB monitoring in 1995. This represents a notable increase from 7.5 million reported in 2022, placing TB again as the leading infectious disease killer in 2023, surpassing COVID-19.
https://www.who.int/news/item/29-10-2024-tuberculosis-resurg...
As well as in the US:
> After declining for three decades, tuberculosis (TB) rates in the U.S. have been increasing steadily since 2020, according to a new report from the Centers for Disease Control and Prevention. It’s a disturbing trend given that 1.5 million die from TB every year, making it the world’s most infectious killer.
https://www.nationalgeographic.com/science/article/us-tuberc...
It's been a big story since the 1980s, IIRC. I remember in college in the 1990s a biologist friend explaining that TB was the greatest disease threat to public health and it was being completely ignored.
Frankly, it's hard to get worked up about it. Notwithstanding that it is a serious public health threat, there's a strong political rhetoric aspect to the discussion, both in the popular and professional spheres. It's unfortunate. In the 1980s and 1990s it was all about how Reagan decimated our public health infrastructure. The arguments aren't per se wrong, but it's difficult to gauge relevance and prioritization about the threat of TB given how part of the medical and scientific community seem to have been border-line crying wolf for 40 years. Discussion centers around absolute numbers. Tell me what the per capita relationship looks like, especially per capita among the populations most vulnerable to acquisition and disease, and what the long-term trends look like. I see this in a lot of other adjacent public health discussions tainted by political hand wringing, such as food insecurity, etc--lots of absolute numbers. But global populations are growing. The US, for example, grew by 80 million people, or 30%, between 1990 and 2020. That's not to deny that tuberculosis is a growing problem, but we have many problems. And the constant drum beat of alarm causes some parts of the community to (increasingly) react in counterproductive ways. From an individual moral standpoint, that's on them, but from an epidemiological and sociological perspective, maybe the professionals bear a little blame, too, at least in terms of communication. We could all do better.
A common bacteria with airborne spread and extremely drug resistant variants in the wild can hardly be characterized this way.
However, it's extremely fair to say that this is not a new issue that has only become apparent over the past week.
> But unfortunately the current administration has decided an ideological purification is more important than keeping the American public apprised of threats to their health.
Looking at the CDC's Morbidity and Mortality Weekly Report, this doesn't actually appear to be true. Going by that link you can read past MMWR reports, and they aren't (from everything I can see) doing weekly tracking of outbreaks, but rather publishing various articles about diseases the way a science journal would. I couldn't find anything about the Kansas tuberculosis outbreak in the most recent reports, so I wouldn't be surprised if we don't see anything about it in the next few MMRW reports.
And yeah, I'm aware a bigger factor in this freeze was hiding the very obvious Bird Flu pandemic. Can't hide the eggs getting more expensive though.
I think this + bad luck, really.
Eggs more expensive doesn't matter any more.
And yes. It really doesn't matter in the grand scheme of things but was such a common rationale for those who voted Trump. I'm shocked that he did not in fact keep a promise thst would have benefitted the working class.
- SARSv2 (aka Covid-19) happened after Trump disbanded the team that contained SARSv1.
- During COVID, the west suspended polio vaccination programs in developing regions, so now polio outbreaks are a thing again.
- Antivaxxers in NYC caused a massive measles outbreak a few years ago.
Etc, etc.
And no country of significant size avoided it, regardless of whether they were led by Trump or not.
There are cough other reasons for that as well:
https://www.scientificamerican.com/article/how-cia-fake-vacc...
Blaming Trump for COVID-19 makes no sense for other reasons too. There are so many other people to blame first. Fauci for funding GoF research at WIV through EHA. The CCP for being secretive and denying there was an outbreak for a while and not allowing investigations in Wuhan for over a year. The WHO for repeating CCP propaganda like claiming there was no human to human transmission roughly fourth months after the first scientists fell ill at WIV. Do you remember Pelosi and democrats downplaying the pandemic and accusing those who wanted to close borders of racism? She apparently had no regrets about all that:
https://www.foxnews.com/politics/pelosi-no-regrets-initial-c...
With all of this how can blame be placed on Trump? If anything his Operation Warp Speed program bailed out the planet from pandemic (with great work from vaccine manufacturers of course).
His views most certainly aren’t what a majority of people want, and he doesn’t try to expand by doing things the majority want. If anything he paints those not completely in his camp, which is the vast majority of Americans, as an enemy.
I'm not sure what you gain by telling yourself that.
I could just as easily assert, without any evidence (i.e., like you), that every single person who didn't vote loves Trump and supports all his policies.
> If anything he paints those not completely in his camp, which is the vast majority of Americans, as an enemy.
That has nothing to do with whether people support him. 20 or more (exact number varies on the reporting) women say that he sexually assaulted them, he was convicted of one sexual assault, and yet white women still voted for him.
Maybe in countries with multiple parties, proportional representation (or the like), and mechanisms to encourage voting like a holiday for elections.
But, everywhere else? It's a crapshoot..low turnout also doesn't help.
TIL Most voters don't have well defined policy preferences. Nor can they correctly associate political parties with their stated policy positions.
That doesn't mean they don't want services, that means that in addition to 74 million that voted against trump, 90 million more also didn't want him.
(It's like NULL values in SQL, only much worse because it's in real life.)
The majority of people wanted this.
Because there's only been one reported car in 2025 in Kansas, I'd be surprised...
1. Is there an argument here that the CDC's Morbidity and Mortality Weekly Report's unbroken publication record is so important it should switch votes?
2. They probably still filled the report in, so there is a chance it eventually gets published. No need to abandon hope yet.
“Democracy is the theory that the common people know what they want, and deserve to get it good and hard.”
Is there any reason why Kansas would be different than other states in particular?