Even in this narrow context, the cuts are indiscriminate in their domain. Moreover, they are rolled out aggressively, carelessly, and abruptly -- a lot of "masculine energy." Science takes years and requires long-term planning. This move just pulls the carpet out; there absolutely is no need for this degree of urgency other than political gain.
These organizations can and will adapt. But as I said in my OP, the real, lasting damage is in prestige. In the meantime, scientists all over the world thinking about working in the US will think twice. Young adults thinking about becoming research physicians and doing biomedical research will think twice. Researchers making peanuts working at universities doing this research will go work in pharma on more lucrative projects.