It's significant that U. Pitt. chose to stop admitting students rather than starting to lay off administrators.
If you build a good lab which has versatile equipment to address many use-cases, the indirect costs will be high.
Private industry is charging/billing cost + margin for profit.
University is saying X is allocated for research, Y is allocated to keep the lights running for the facility and pay for students. The students are generally funded by research, not the University. No research money, no money for students.
Two S&P 100s, one 500.
Academia is not "private industry."
Those overhead fees go to fund that, so universities don’t have to be even mere full of nepo baby donor legacy admissions than they already are