I don't doubt that you can physically carry big enough of a payload on an intercept trajectory, I just doubt that a clandestinely manufactured quadcopter will be able to either autonomously track its target (not big enough to carry a radar) or be controllable from 20 miles away (even in Ukraine EW is pervasive).
More realistically they'd try to modify the targeting of their existing AtoA and send fighters. Which is kinda like a bunch of big drones carrying small ones.