Computer networking is not the same. Our networks will not explode. I will grant you that they can be shite if not designed properly but they end up running slowly or not at all, but it will not combust nor explode.
If you get the basics right for ethernet then it works rather well as a massive network. You could describe it as an internetwork.
Basically, keep your layer 1 to around 200 odd maximum devices per VLAN - that works fine for IPv4. You might have to tune MAC tables for IPv6 for obvious reasons.
Your fancier switches will have some funky memory for tables of one address to other address translation eg MAC to IP n VLAN and that. That memory will be shared with other databases too, perhaps iSCSI, so you have to decide how to manage that lot.
