FWIW, I'm a huge fan of both John Lee Hooker and Jimmy Reed, who had similar vamp-based playing styles and were untutored, couldn't read music, &c. One of my guitar teachers knew Hooker and he even imparted "the secret of the guitar" to him, which he then passed down to me.
But yeah, feel, instinct, and having good ears can carry you a long way especially for solo artists. I'm still glad I can read music and wouldn't trade that for (almost) anything, though.