I'll add a bit more nuance to that - people don't always read every word of a newspaper article. That's fine, it's why the inverted pyramid [0] model is used. If there's a big headline (Neil Armstrong Dies) and a single photo (the one of Buzz Aldrin) and the fact it's not a photo of Armstrong is in a little caption, it's going to contribute to the misconception that the photo of Aldrin is actually a photo of Armstrong.
Contributing to misconceptions is bad and should be avoided. Luckily this is easy - just use the photo of Armstrong in the lunar lander.
On the other hand, it's unlikely anyone would mistake Leonardo and the woman in the Mona Lisa so it wouldn't seem so bad to me!
I might have some bias here as someone who reads primarily online media, but I haven't observed most venues limiting themselves to a single photo.
[0] http://science.time.com/2012/08/25/remembering-neil-armstron... [1] http://www.standard.co.uk/news/world/neil-armstrong-modest-h... [2] http://www.telegraph.co.uk/science/space/9501410/Neil-Armstr... [3] http://www.guardian.co.uk/science/2012/aug/26/neil-armstrong... [4] http://articles.timesofindia.indiatimes.com/2012-08-26/us/33... [5] http://www.thestar.com/news/world/article/1247118--neil-arms... [6] http://www.washingtonpost.com/national/health-science/neil-a... [7] http://www.bbc.co.uk/news/world-us-canada-11162858 [8] http://www.bangkokpost.com/learning/learning-from-news/30958...