CO2 sensors are generally pretty accurate, but PM2.5 sensors are notoriously prone to false spikes usually caused by dust in or around the sensor: https://www.reddit.com/r/Awair/comments/10r1uyo/inaccurate_p... or https://forum.airgradient.com/t/unusual-pm2-5-readings-on-ne... or https://community.purpleair.com/t/what-to-do-about-incorrect...
My guess is it's likely a sensor in a hotel room accumulates dust over time, leading to high PM2.5 measurements maybe when something (eg. suitcase) bumps against the case, shaking the accumulated dust and releasing it around the sensor.