Any sort of business that might want to serve from a customized LLM at scale and doesn't need the smartest model possible, or hobbyist/researcher experiments. If you can get an agentic framework to work on a problem with a local model, it'll almost certainly work just as well on a cloud model. Again, speaking mostly people to already have a xx90 class GPU sitting around. Smoke 'em if you've got 'em. If you don't have a 3090/4090/5090 already, and don't care about privacy, then just enjoy how the improvements in local models are driving down the price per token of non-bleeding-edge cloud models.